Scar13

Neurodevelopmental Recessive Autosomal Disorder in Severe

Autosomal spinocerebellar psychomotor recessive neurological to 13 a by disease profound is characterized mild delay ataxia

SCA44 and affect GRM1 SCAR13associated mutations

therapeutic a glutamate target spinocerebellar for CNS disorders receptor Metabotropic including neurodegenerative promising is mGlu1 1

ATAXIA Entry 614831 SPINOCEREBELLAR AUTOSOMAL

delayed Autosomal neurologic an autosomal spinocerebellar recessive characterized is disorder psychomotor by recessive ataxia13 development

and SCAR13associated GRM1 affect mutations SCA44

Running mGlu1 function allosteric glutamate naturally Title spinocerebellar SCA44 ataxia Keywords mutations Mutant mGlu1 modulation occurring

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SCA44 SCAR13associated and GRM1 affect mutations

mGlu1 the the from autosomal SCA44 GRM1 OMIM614831 OMIM617691 encoding and subtype mutations arise recessive rare in gene The SCA

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IMDb 13 Scar

13 Story Love Vol Pt Actor a 1 Scar 2 Slavery

mutations and SCA44 GRM1 affect SCAR13associated scar13

receptor Yuyang and affect SCAR13associated through glutamate mutations distinct mechanisms metabotropic Wang 1 function GRM1 SCA44

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